Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Cys1&Cys15 bridge , Cys3&Cys11 bridge)
Size : 1
P1(RMB) : 1747
MW : 2492
One letter sequence : CSCSSLMDKECVYFCHLDIIW (C1&C15 bridge , C3&C11 bridge)
Molecular Formula : C109H159N25O32S5
Description : Potent vasoconstrictor that acts on endothelia cells and on the underlying smooth muscle cells as a modulator of vascular tone. ET-1 displays selectivity for ETA receptor.
Literature Reference : A. Inoue, et al., PNAS, 80, 2863 (1989); M. Yanagisawa et al., TIPS, 10, 374 (1989); G.J. Price et al., Nucleic Acids Res., 18, 3658 (1991)
Cas : [117399-94-7]
