Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH2(Cys&Cys bridge)
Size : 1
P1(RMB) : 582
MW : 1918.3
One letter sequence : Ac-NWCKRGRKQCKTHPH-NH2(Cys&Cys bridge)
Molecular Formula : C81H128N32O19S2
Description : Cyclized peptide that binds strongly to heparin and inhibits binding of 125 I-labeled APP to heparin (IC50= 10-7M). It also blocks the heparin sulfate proteoglycan-dependent stimulatory effect of APP on neurite outgrowth.
Literature Reference : D.H. Small et al., J. Neurosci., 14, 2117 (1994)
Cas :
