Ac-Nle-cyclo(Asp-His-DPhe-Arg-Trp-Lys-NH2)Peptide beta bond Asp3&Lys8 bridge
Size : 1
P1(RMB) : 306
MW : 1024.2
One letter sequence : Ac-Nle-cyclo(DHfRWK-NH2)Peptide beta bond D3&K8 bridge
Molecular Formula : C50H69N15O9
Description : Cyclic MSH analog that is a potent full agonist of the melanocortin-3 and melanocortin-4 receptors (MC3-R and MC4-R). MTII is a useful tool in the study of the agouti obesity syndrome and the role of melanocortinergic neurons in feeding.
Literature Reference : V.J. Hruby et al., J. Med. Chem., 38, 3435 (1995)
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