DPhe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-cyclo(Glu-Ala-His-Lys)-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH2
Size : 1
P1(RMB) : 1011
MW : 3563.2
One letter sequence : fHLLREVLE-Nle-ARAEQLAQ-cyclo(EAHK)NRKL-Nle-EII-NH2
Molecular Formula : C161H269N49O42
Description : A new CRF antagonist (cyclo(30/33) that, when injected into the CSF at low doses (1-10ug), results in antagonistic action against CRF and stress-related alterations of gastrointestinal motor function, without an intrinsic effect in these in vivo systems.
Literature Reference : V. Martinez et al., J. Pharmacol. Exp. Ther., 280(2), 754 (1997)
Cas :
