Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asp-Val-Gly-Ala-Gly-Thr-Pro-NH2Peptide bond Ser1&Asu6 bridge
Size : 1
P1(RMB) : 1195
MW : 3363.9
One letter sequence : SNLST-Asu-VLGKLSQELHKLQTYPRTDVGAGTP-NH2 Peptide bond Ser1&Asu6 bridge
Molecular Formula : C147H242N42O47
Description : Carbocalcitonin, the amino-suberic acid analog of eel calcitonin, has all the biological properties of the corresponding natural calcitonin. The substitution of the disulfide bond of natural calcitonins with an ethylene bridge in the 1-7 N-terminal position gives elcatonin greater stability and excellent tolerability when used in vivo.
Literature Reference : A. Caniggia et al., Minerva Medica , 74, 993 (1983); Italian Osteoporosis Network, Current Therapeutic Res., 45, 502 (1989)
Cas :
