Chinese Peptide Company

ATMP-005B

Dermaseptin
Ala-Leu-Trp-Lys-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asp-Thr-Ile-Ser-Gln-Gly-Thr-Gln
Size : 1
P1(RMB) : 1195
MW : 3455.1
One letter sequence : ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ
Molecular Formula : C152H257N43O44S2
Description : Peptide that is isolated from skin extracts of the South American arboreal frog, Phyllomedusa Sauvagei. It is a strongly basic, water-soluble, thermalstable nonhemolytic compound, nonhemolytic peptide that exhibits highly potent antimicrobial activity against pathogenic fungi at micromolar concentration. A potential amphiphatic alpha-helix structure can probably function by membrane permeabilization.
Literature Reference : A. Mor et al., Biochemistry, 30, 8824 (1991)
Cas :
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