Size : 1
P1(RMB) : 91.95
MW : 784.8
One letter sequence : Ac-WEHD-AMC
Molecular Formula : C38H40N8O11
Description : With a Kcat/Km of 3.3•106M-1s-1 this fluorogenic caspase-1 substrate is cleaved 50-fold more efficiently than CASP-010. This phenomena shows that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.
Literature Reference : T.A. Rano et al., Chem. Biol. 4, 149 (1997)
Cas : [189275-74-9]
