Size : 5
P1(RMB) : 460
MW : 492.5
One letter sequence : Ac-YVAD-CHO
Molecular Formula : C23H32N4O8
Description : Tetrapeptide aldehyde, a potent, specific, reversible inhibitor of caspase-1 (ICE) that displays a Ki of 0.2 ±0.1 nM for recombinant human caspase-1.
Literature Reference : N.A. Thornberry et al., Nature 356, 768 (1992); S.M. Molineaux et al., Proc. Natl. Acad. Sci. USA, 90, 1809 (1993); N.P.C. Walker et al., Cell, 78, 343 (1994)
Cas : [143313-51-3]
