Size : 1
P1(RMB) : 153
MW : 355.8
One letter sequence : Boc-D(OBzl)-CMK
Molecular Formula : C17H22ClNO5
Description : Inhibitor that penetrates cells and binds covalently to the active site of caspase-1 (ICE). At a concentration of 2.5 µM, it blocks caspase-1-mediated processing of mature interleukin-1beta in a monocytic cell line by 85% without influencing tumor necrosis factor processing.
Literature Reference : N.Boudreau et al., Science, 267, 891 (1995)
Cas : [172702-58-8]
