Chinese Peptide Company

CASP-035A

Caspase-1 Inhibitor V
Z-Val-Ala-DL-Asp(OMe)-FMK
Size : 0.5
P1(RMB) : 306
MW : 467.5
One letter sequence : Z-VA-DL-Asp(OMe)-FMK
Molecular Formula : C22H30F1N3O7
Description : ICE-like protease inhibitor that blocks all features of apoptosis: morphological changes, cleavage of caspase-3 (CPP32/Yama/Apopain) and poly(ADP-ribose) polymerase, lamin B degradation and DNA fragmentation.
Literature Reference : T. Shimizu et al., Leukemia, 11, 1238 (1997); H. Hara et al., Proc. Natl. Acad. Sci. USA, 94, 2007 (1997)
Cas :
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