Size : 1
P1(RMB) : 368
MW : 1431.48
One letter sequence : FITC-C6-YVADAP-Lys(Dnp)
Molecular Formula : C68H78N12O21S
Description : Specific substrate for the determination of caspase-1 and caspase-1-like enzyme activities. Cleavage of this peptide substrate at the P1 Asp residue causes a continuous fluorescent assay, thus useful both in FACS and fluorescence microscopy experiments. Caspase-3 is only weakly active on this substrate.
Literature Reference : H.J. Korting et al., Virologie, 28, 41 (1977); A. Chersi et al., Biochim. Biophys. Acta, 1034, 333 (1990)
Cas :
