Size : 1
P1(RMB) : 153
MW : 502.5
One letter sequence : Ac-IETD-CHO
Molecular Formula : C21H34N4O10
Description : Peptide aldehyde that corresponds to one of the cleavage sites of the inactive 32 kD caspase-3 precursor (amino acids 172-175). In a concentration range of 0.5 µM, it blocks the formation of the p17 subunit and concomitantly induces the accumulation of the 32kD precursor.
Literature Reference : Z. Han et al, J. Biol Chem., 272, 13422 (1997); M.Garcia-Calvo et al., J. Biol. Chem., 273, 32608 (1998)
Cas : [191338-86-0]
