Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser
Size : 1
P1(RMB) : 828
MW : 3157.5
One letter sequence : GWTLNSAGYLLGPHAVGNHRSFSDKNGLTS
Molecular Formula : C139H210N42O43
Description : Human galanin, originally been isolated from colon and pituitary, that activates the rat galanin receptor and inhibits acetylcholine release, glutamate release and carbachol-stimulated phosphatidylinositol hydrolysis in the hippocampus. Recent studies indicated that galanin is also linked to behavioral and cognitive deficits in Alzheimer's disease.
Literature Reference : W.E. Schmidt et al., PNAS, 88, 11435 (1991)
Cas :
