His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
Size : 1
P1(RMB) : 582
MW : 3297.7
One letter sequence : HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2
Molecular Formula : C149H226N40O45
Description : GLp-1 fragment that is isolated from the lower small intestine and is presently regarded to be the most important incretin hormone. It shows a strong insulinotropic effect that is mediated by receptors expressed in the pancreatic beta-cells. It is proposed to be a novel therapeutic strategy for non-insulin-dependent (type 2) diabetes mellitus and associated neuropathy.
Literature Reference : G. Bell et al., Nature, 304, 368 (1983)
Cas : [107444-51-9]
