Size : 1
P1(RMB) : 215
MW : 920.2
One letter sequence : IMQVPFSV
Molecular Formula : C43H69N9O11S1
Description : Peptide that contains modified sequence of the gp 100 epitope gp(209-217), in which a methionine replaced the natural threonine at position 2. This peptide also binds to the HLA-A2 molecule with greater affinity than the unmodified peptide and has exhibited a good ability to stimulate melonomareactive cytotoxic T lymphocytes (CTLs) in vitro when used for sensitization of peripheral blood mononuclear cells. This synthetic peptide holds promise for the development of novel cancer immunotherapies.
Literature Reference : S.A. Rosenberg et al., Nature Med<$>., 4, 321 (1998)
Cas :
