DABCYL-GABA-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Glu(EDANS)-Ala-Lys-NH2
Size : 0.5
P1(RMB) : 460
MW : 2078.5
One letter sequence : Dabcyl-GABA-RPKPVE-Nva-WR-Glu(Edans)-AK-NH2
Molecular Formula : C99H144N28O20S1
Description : Selective fluorogenic matrix metalloproteinase (MMP) substrate with the following Kcat/Km value for MMP-3 (Stromelysiin-1) is 29.0 M-1s-1, for MMP-13 13.0 M-1s-1, and for MMP-9 7.5 M-1s-1 (at pH = 7.5, 25°C). The fluorescence increase is measured using an wavelength of 360 nm and an emission wavelength of 490 nm. No activity against this substrate could be measured with MMP-1, MMP-7, and MMP-8.
Literature Reference : Beekman, B., et al., 1997. FEBS Lett 418, 305.
Cas :
