Ile-Thr-Ser-Phe-Glu-Glu-Ala-Lys-Gly-Leu-Asp-Arg-Ile-Asn-Glu-Arg-Met-Pro-Pro-Arg-Arg-Asp-Ala-Met-Pro
Size : 1
P1(RMB) : 766
MW : 2930.4
One letter sequence : ITSFEEAKGLDRINERMPPRRDAMP
Molecular Formula : C124H205N39O39S2
Description : Amino acid sequence of this peptide that is identical with the C-terminal region of the calmodulin-bing domain. It inhibits Mn2+-stimulated calcineurin activity (IC50 = 10 m M) using [32P] myosin light chain as a substrate but has no effect on Ni2+ -stimulated activity.
Literature Reference : Y. Hashimoto et al., J. Biol. Chem., 265, 1924 (1990)
Cas :
