Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2
Size : 1
P1(RMB) : 1011
MW : 2846.5
One letter sequence : GIGAVLKVLTTGLPALISWIKRKRQQ-NH2
Molecular Formula : C131H229N39O31
Description : 26-residue polypeptide isolated from bee venom that binds calmodulin in a Ca2+ dependent manner, activates phospholipase A2, and inhibits protein kinase C (IC50 = 5-7 m M) by binding to the catalytic domain in a Mg-ATP sensitive manner. IC50 of 1-4 micro-M.
Literature Reference : Raynor et al., J. Biol. Chem., 266, 2753 (1991);
Schweitz, Toxicon, 22, 308 (1984)
Cas :
