Size : 0.5
P1(RMB) : 276
MW : 1559.9
One letter sequence : YGRKKRRQRRR
Molecular Formula : C64H118N32O14
Description : This is the most characterized fragment of the HIV transactivator protein (TAT). This arginine-rich TAT peptide penetrates plasma membrane directly, but not through endocytosis, and has been proven to promote the entry of nucleic acids into several cell types.
Literature Reference : C. Rudolph, et al.,JBC Papers in Press, M211891200, (2003)
V.P. Torchilin, et al., PNAS, 100, 1972-1977, (2003)
Wang, H. et al. J. Clin. Invest. 109, 1463 (2002)
Ziegler et al. Biochem. 44, 138 (2005)
Wender, PA. et al. Proc. Natl. Acad. Sci. USA 97, 13003 (2000).
Cas :
