Size : 0.5
P1(RMB) : 153
MW : 678.8
One letter sequence : Ac-LPFFD-NH2
Molecular Formula : C35H46N6O8
Description : beta-sheet breaker peptide iAbeta5p that crosses the blood-brain barrier at a higher rate than most proteins and peptides. It is known to be selectively taken up by the brain, thereby suggesting that the peptide is being specifically transported to the brain. A significant increase in neuronal survival and decrease in brain inflammation associated with the reduction of amyloid plaques in two different transgenic Alzheimer's disease (AD) models is additionally reported for this pentapeptide. Abeta (1-42) Fibrillogenesis Inhibitor.
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