Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg
Size : 1
P1(RMB) : 1073
MW : 2005.2
One letter sequence : R-E(EDANS)-EVNLDAEF-K(DABCYL)-R
Molecular Formula : C91H129N25O25S1
Description : Fluorogenic substrate for pro-memapsin-2 containing the beta-secretase site of the Swedish mutation of APP. The kinetic parameters at pH 4.5 are Km = 5.4 µM and kcat = 0.24 min-1.
Literature Reference : A.K. Ghosh et al., J. Amer. Chem. Soc., 122, 3522 (2000); J. Ermolieff et al., Biochemistry, 39, 12450 (2000)
Cas : [310427-94-2]
