Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH2(Cys1&Cys11,Cys3&Cys15 Bridge)
Size : 0.5
P1(RMB) : 880
MW : 2027.37
One letter sequence : CNCKAPETALCARRCQQH-NH2(Cys1&Cys11,Cys3&Cys15 Bridge)
Molecular Formula : C79H131N31O24
Description : Apamin, isolated from bee venom, the smallest neurotoxic polypeptide, and also the only peptide can pass the blood-brain barrier. This peptide blocks specifically the Ca2+-dependent K+ channels.
Literature Reference : J.Van Rietschoten et al., Eur. J. Biochem., 56, 35 (1975)
M.Hugues et al., Proc. Natl. Acad. Sci. USA, 79, 1308 (1982)
Cas : 24345-16-2
