Size : 5
P1(RMB) : 612
MW : 881.09
One letter sequence : VKFGVGFK
Molecular Formula : C44H68N10O9
Description : The peptide acts as a calmodulin agonist, interacts with the calmodulin EF-hand motif, the Ca2+ binding site. CALP-3 activates the phosphodiesterase in the absence of Ca2+ and inhibits cytotoxicity and apoptosis in a Ca2+ mediated manner.
Literature Reference : M.Villain et al., J. Biol. Chem., 275, 2676 (2000)
M.K.Manion et al., FASEB J., 14, 1297 (2000)
R.Ten Broeke et al., FASEB J., 15, 1831 (2001)
R.Ten Broeke et al., Eur. J. Pharmacol., 476, 151 (2003)
Cas : 261969-05-5
