Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu
Size : 1
P1(RMB) : 473
MW : 2183.6
One letter sequence : ARTKQTARKSTGGKAPRKQL
Molecular Formula :
Description : This peptide is the N-terminal of H3 histone (1-20). It has nearly identical acetylation efficiency as the H4 peptides. Acetylation of histones is associated with transcription activity, constitutes a post-translational mark recognized by specific chromatin factors, and prevents salt-induced folding of nucleosome arrays in vitro. Multisubunit histone acetyltransferase (HAT) complexes recognize and perform efficient acetylation on nucleosome substrates.
Literature Reference : Berndsen, C. et al. Biochem. 46, 2091 (2007).
Cas :
