Ala-Thr-Lys-Ala-Ala-Arg-Lys(Me3)-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Lys(Biotin)
Size : 0.25
P1(RMB) : 408
MW : 2902.4
One letter sequence : ATKAAR-K(Me3)-SAPATGGVKKPHRYRPG-K(Biotin)
Molecular Formula :
Description : This peptide is the fragment of Histone H3 (21-44) tri-methylated at Lys27 with an additional C-terminal Lys and biotinylation on the -epsilon side chain of this Lys. Tri-methylation of Lys27 promotes Polycomb protein (Pc)-chromatin association and is associated with heterochromatin assembly and gene silencing.
Literature Reference : Zhang, X. et al. Nat Struct Mol Biol 14, 869 (2007);
Min, J. et al. Genes Dev 17, 1823 (2003).
Cas : N/A
