Size : 5
P1(RMB) : 1090
MW : 1003.2
One letter sequence : Ac-RRWWCR-NH2
Molecular Formula : C45H66N18O7S
Description : Antileukinate, Ac-RRWWCR-amide, inhibits the specific binding of 125I-labeled IL-8 to neutrophils with an apparent Ki = 10 µM. The hexapeptide also significantly suppresses neutrophil chemotaxis induced by 10 nM IL-8 at a concentration of 50 µM. The inhibition is specific for IL-8.
Literature Reference : S.Hayashi et al., J. Immunol., 154, 814 (1995)Y.Fukuno et al., Cytokine, 22, 116 (2003)X.Lin et al., Am. J. Physiol. Lung Cell. Mol. Physiol., 289, L583 (2005)
Cas : 138559-60-1
