Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Trifluoroacetate salt
Size : 1
P1(RMB) : 254
MW : 1626.84
One letter sequence : LPNYNWNSFGLRF-NH2
Molecular Formula : C78H107N21O18
Description : An LRF-amide motif containing fragment of malignant melanoma metastasis suppressor KiSS-1. It bound with low nanomolar affinity to the rat and human G protein-coupled receptor GPR54 expressed in Chinese hamster ovary K1 cells and stimulated PIP2 hydrolysis, Ca2+ mobilization, arachidonic acid release, ERK1/2 and p38 MAP kinase phosphorylation, and stress fiber formation but inhibited cell proliferation.
Literature Reference : M.Kotani et al., J. Biol. Chem., 276, 34631 (2001)
R.A.Silvestre et al., J. Endocrinol., 196, 283 (2008)
Cas : 374675-18-0
