Size : 25
P1(RMB) : 4600
MW : 642.82
One letter sequence : Ac-PLA-[(S)-2-mercapto-pentanoyl]-W-NH2
Molecular Formula : C32H46N6O6S
Description : A stromelysin-1 substrate, which is also hydrolyzed by two other matrix metalloproteinases, collagenase and gelatinase, and by the bacterial metalloproteinase thermolysin. The thiopeptolide Ac-PLA-psi[COS]Nva-W-amide mimics the MMP-3 cleavage site Leu-Ala-Nva-Trp
Literature Reference : R.L.Stein and M.Izquierdo-Martin, Arch. Biochem. Biophys., 308, 274 (1994)W.Pan et al., J. Biol. Chem., 278, 27820 (2003)
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