Glp-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Val-Gly-Asp-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Size : 1
P1(RMB) : 1490
MW : 4125.7
One letter sequence : Glp-FRHDSGYEVHHQKLVFFAEVGDSNKGAIIGLMVGGVV
Molecular Formula :
Description : The fibrils in the plaques formed in the brains of patients with Alzheimer’s disease contain significant amounts of truncated Aß proteins. This fragments contain an N-terminal pyroglutamic acid. The g-carboxy group of glutamic acid forms a cyclic bond with the free N-terminal amino group to form pyroglutamate
Literature Reference : Ref: Mok, SS. et al. J. Neurosci. Res. 61, 449 (2000); Russo, C. et al. Nature. 405, 531 (2000)
Cas :
