Ile-Leu-Gln-Arg-Gly-Ser-Gly-Thr-Ala-Ala-Val-Asp-Phe-Thr-Lys-Lys-Asp-His-Thr-Ala-Thr-Trp-Gly-Arg-Pro-Phe-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2
Trifluoroacetate salt
Size : 0.5
P1(RMB) : 838
MW : 3791.34
One letter sequence : ILQRGSGTAAVDFTKKDHTATWGRPFFLFRPRN-NH2
Molecular Formula : C173H265N53O44
Description : This peptide was originally isolated from rat brain as an endogenous ligand for two orphan G protein-coupled receptors FM-3/GPR66 and FM-4/TGR-1, which have been identified as neuromedin U (NMU) receptors. hNMS-33 is specifically expressed in the suprachiasmatic nuclei (SCN) of the hypothalamus. It has been shown that NMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions.
Literature Reference : K.Mori et al., EMBO J., 24, 325 (2005)
Cas :
