Size : 25
P1(RMB) : 748
MW : 748.88
One letter sequence : SFLLRN
Molecular Formula : C34H56N10O9
Description : This peptide is the fragment 42-47 of the thrombin receptor, which acts as a thrombin receptor activator. It is effective in causing tyrosine phosphorylation, inhibition of cAMP formation, and an increase in cytosolic Ca2+.
Literature Reference : L.F.Brass et al., J. Biol. Chem., 269, 2943 (1994)
R.Kaufmann et al., NeuroReport, 9, 709 (1998)
B.A.Olson et al., Pharmacology, 58, 200 (1999)
H.Andersen et al., Proc. Natl. Acad. Sci. USA, 96, 11189 (1999)
R.Kaufmann et al., J. Neurooncol., 42, 131 (1999)
C.-C.Wu et al., Br. J. Pharmacol., 130, 1289 (2000)
H.Shankar et al., Blood, 104, 1335 (2004)
J.C.Resendiz et al., J. Thromb. Haemost., 5, 2484 (2007)
Scarborough, RM. et al. J. Biol. Chem. 267, 13146 (1992); Ahmad, S. and PN. Walsh, Biochem. 44, 13858 (2005); Buergler, M. et al. J. Thromb. Thrombolysis 19, 115 (2005).
Cas : 141136-83-6
