Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-NH2
Trifluoroacetate salt
Size : 5
P1(RMB) : 1540
MW : 1738.96
One letter sequence : SFLLRNPNDKYEPF-NH2
Molecular Formula : C81H119N21O22
Description : This peptide can inhibit monocyte spreading on fibronectin-coated slides. The rapidly induced withdrawal of pseudopodial processes and rounding of the cells is accompanied by nitric oxide and endothelin-1 release. Spreading might be inhibited by autocrine endothelin-1 release and subsequent endothelin B receptor-dependent nitric oxide production
Literature Reference : K.D.Srivastava and H.I.Magazine, J. Immunol., 161, 5039 (1998)
J.R. Ngaiza and E.A. Jaffe, Biochem. Biophys. Res. Commun., 179, 1656 (1991).
D.M. Feng, D.F. Veber, T.M. Connolly, C. Condra, M.J. Tang, and R.F. Nutt, J. Med. Chem.,38,4125 (1995).
Cas : 141923-36-6
