Biotin-Lys-Gly-Trp-His-Leu-Lys-Ser-Lys(Me1)-Lys-Gly-Gln-Ser-Thr-Ser-Arg-His-Lys-Lys-Leu-Met-Phe-Lys-Thr-Glu-Gly-Pro-Asp-Ser-Asp-NH2
Size : 1
P1(RMB) : 1526
MW : 3582.2
One letter sequence : Biotin-KGWHLKS-K(Me1)-KGQSTSRHKKLMFKTEGPDSD-NH2
Molecular Formula :
Description : This is human tumor suppressor protein p53 (368-393) monomethylated at Lys373 and biotinylated through a KGW linker at its N-terminus. Methylation at Lys373 is catalyzed by G9a and Glp lysine methyltransferases and is associated with inactive p53.
Literature Reference : Krishnan, S. et al. ChemBioChem 12, 254 (2011)
Huang, J. et al. J Biol Chem 285, 9636 (2010).
Cas :
