Size : 1
P1(RMB) : 275
MW : 1251.5
One letter sequence : ETFSDLWKLL
Molecular Formula :
Description : This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development.
Literature Reference : Wang, Y. et al. J. Biol. Chem. 281, 24803 (2006)
Kanovsky, M. et al. PNAS 98, 12438 (2001).
Cas :
