Lys-Thr-Asn-Met-Lys-His-Met-Ala-Gly-Ala-Ala-Ala-Ala-Gly-Ala-Val-Val-Gly-Gly-Leu-Gly
Trifluoroacetate salt
Size : 1
P1(RMB) : 503
MW : 1912.3
One letter sequence : KTNMKHMAGAAAAGAVVGGLG
Molecular Formula : C80H138N26O24S2
Description : This peptide increases membrane microviscosity, intracellular Ca2+ concentration and cell migration in circulating leucocytes, and oxygen production in monocytes and neutrophils. It also induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell lines. PrP (106–126) stimulates leucocyte migration in a dose-dependent manner.
Literature Reference : Diomede, L. et al. Biochem. J. 320, 563 (1996)Florio, T. et al. J. Neurosci. Res. 54, 341 (1998).
Cas : 148439-49-0
