Chinese Peptide Company

PPEP-004

-epsilon-V1-2, -epsilon-PKC Inhibitor
Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr
Size : 1
P1(RMB) : 275
MW : 844
One letter sequence : EAVSLKPT
Molecular Formula :
Description : This peptide is derived from residues 14-21 of protein kinase C C2 (-epsilonPKC C2). This peptide specifically inhibits -epsilonPKC by disrupting PKC binding to its receptor, RACK2. -epsilonPKC mediated signal transduction plays a role in cell proliferation, differentiation, and apoptosis.
Literature Reference : Lamy, C. et al. Tetrahedron Lett 46, 6177 (2007) Brandman, R. et al. J. Biol. Chem. 282, 4113 (2007)
Cas :
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