Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg
Size : 1
P1(RMB) : 830
MW : 2282.7
One letter sequence : R-E(EDANS)-IHPFHLVIHT-K(DABCYL)-R
Molecular Formula :
Description : This peptide is a renin substrate (angiotensinogen) labeled with EDANS/ DABCYL FRET pair for renin activity studies. The renin-angiotensin system (RAS), acting through type 1 angiotensin (AT1) receptors, is a master regulator of fluid homeostasis.
Literature Reference : Crowley, S. et al. J. Clin. Invest. 115, 1092 (2005); Holzman, T. et al. J. Protein Chem. 9, 663 (1990).
Cas :
