Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly (Disulfide bridge: 2-10 and 4-8)
Size : 5
P1(RMB) : 6750
MW : 1145.3
One letter sequence : ACDCRGDCFCG (Disulfide bridge: 2-10 and 4-8)
Molecular Formula : C42H60N14O16S4
Description : This peptide, a double cyclic peptide, binds preferentially to integrins at sites of tumor angiogenesis and inflammed synovium in-vivo, and can be internalized into targeted cells
Literature Reference : Curnis, F. et al. Cancer Res. 64, 565 (2004); Su, Z. et al. Bioconjug. Chem. 13, 561 (2002); Gerlag, M. et al. Arthritis Res. 3, 357 (2001); Ellerby, H. et al. Nature Med. 5, 1032 (1999);
Cas :
